The duration of a One Wales decision is decided on a case-by-case basis. For licensed medicines, it is unlikely to exceed 18 months and would normally be 12 months or until publication/ratification of NICE technology appraisal guidance/AWMSG recommendation. One Wales decisions will be reviewed by OWMAG a minimum of 12 months (maximum of three years) from the date of advice. AWTTC will conduct a literature search and may request outcome data annually for all medicines.