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All Wales HIV-1 antiretroviral therapy prescribing guidelines

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Antiretroviral therapy (ART) is licensed for the treatment of human immunodeficiency virus type 1 (HIV-1). The aim of ART is to suppress the viral load, reduce mortality and morbidity associated with HIV infection, reduce onwards transmission and prevent the development of acquired immune deficiency syndrome. Over the years, treatment outcomes with ART have improved significantly with respect to clinical effectiveness and tolerability.

The purpose of the All Wales HIV-1 antiretroviral therapy prescribing guidelines is to support consistency across Wales in the evidence-based and prudent prescribing of antiretroviral therapy for the treatment of HIV-1. The guidance aims to support clinicians and other healthcare professionals in the pharmacological management of HIV-1 to deliver good prescribing practice, optimise treatment to suppress the viral load while minimising the risk of adverse effects, and improve the person’s health-related quality of life.

All Wales HIV-1 antiretroviral therapy prescribing guidelines 1MB (PDF)

Published - May 2026

Equality and Health Impact Assessment (EqHIA) form

All Wales HIV-1 antiretroviral therapy prescribing guidelines EqHIA - May 2026

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