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pegylated liposomal irinotecan (Onivyde®)

 

Following a full submission

AWMSG advice

Status: Terminated

In combination with oxaliplatin, 5-fluorouracil (5-FU) and leucovorin (LV) for the first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas. This medicine was considered by AWMSG Scrutiny Panel on 07/08/2025. It was considered suitable for full HTA assessment by LOWMAG. Following discussion with the company it was agreed at this time not to proceed with an HTA due to insufficient comparative information.

 

Medicine details

Medicine name pegylated liposomal irinotecan (Onivyde®)
Formulation 4.3 mg/ml concentrate for solution for infusion
Reference number 6200
Indication

As above

Company Servier Laboratories Ltd
BNF chapter Malignant disease & immunosuppression
Assessment type Full
Status Terminated
Scrutiny Panel meeting date 07/08/2025
Date of issue 06/05/2026
NICE guidance

TA1052:Pegylated liposomal irinotecan in combination for untreated metastatic pancreatic cancer (terminated appraisal)

Further information

This medicine was considered by AWMSG Scrutiny Panel on 7 August 2025 and was found suitable for a full HTA assessment via the Licensed Medicines One Wales Medicines Assessment Group (LOWMAG).

A Welsh Patient Access Scheme (WPAS) was agreed in principle through the Commercial Arrangement Scheme Wales Group (CASWG). Following discussion with the company it was agreed, at this time not to proceed with an HTA due to insufficient comparative information. If AWTTC or the company become aware of a significant change, this decision may be reviewed.

 

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