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emicizumab (Hemlibra®)

 

Status: AWMSG assessment in progress

Emicizumab (Hemlibra®) is recommended as an option for use in NHS Wales for the routine prophylaxis of bleeding episodes in patients with haemophilia A (congenital factor VIII deficiency) without factor VIII inhibitors who have moderate disease (FVIII ≥ 1% and ≤ 5%) with severe bleeding phenotype.

This recommendation applies only in circumstances where the agreed commercial access arrangement (CAA) between the MA holder and NHS Wales is utilised or where the list / contract price is equivalent or lower than the CAA price.

 Recommendation and Decision Rationale: emicizumab (Hemlibra) 4742 (PDF, 92Kb)
 Evidence Summary Report: emicizumab (Hemlibra) 4742 (PDF, 121Kb)
 Equality and Health Impact Assessment: emicizumab (Hemlibra) 4742 (PDF, 169Kb)

Medicine details

Medicine name emicizumab (Hemlibra®)
Formulation 150 mg/ml solution for subcutaneous injection
Reference number 4742
Indication

For routine prophylaxis of bleeding episodes in patients with haemophilia A (congenital factor VIII deficiency) without factor VIII inhibitors who have moderate disease (FVIII ≥ 1% and ≤ 5%) with severe bleeding phenotype

Company Roche Products Ltd
BNF chapter Nutrition & blood
Assessment type Limited
Status AWMSG assessment in progress
Scrutiny Panel meeting date 03/11/2025
LOWMAG meeting date 15/04/2026
AWMSG meeting date 20/05/2026
Date of issue 26/05/2026
Commercial arrangement CAA
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