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bortezomib (Velcade®)

 

Following a limited submission

AWMSG advice

Status: Recommended

Bortezomib (Velcade®) 3.5 mg subcutaneous injection is recommended as an option for use within NHS Wales:

  • for the treatment of adult patients with progressive multiple myeloma who have received at least 1 prior therapy and who have already undergone or are unsuitable for haematopoietic stem cell transplantation;
  • in combination with melphalan and prednisone for the treatment of adult patients with previously untreated multiple myeloma who are not eligible for high-dose chemotherapy with haematopoietic stem cell transplantation.
 Final Recommendation: bortezomib (Velcade) 1254 (PDF, 340Kb)
 Appraisal Report: bortezomib (Velcade) 1254 (PDF, 220Kb)

Medicine details

Medicine name bortezomib (Velcade®)
Formulation 3.5 mg powder for solution for subcutaneous injection
Reference number 1254
Indication

In combination with melphalan and prednisone for the treatment of patients with previously untreated multiple myeloma who are not eligible for high-dose chemotherapy with haematopoietic stem cell transplantation; and as monotherapy for the treatment of progressive multiple myeloma in patients who have received at least 1 prior therapy and who have already undergone or are unsuitable for haematopoietic stem cell transplantation

Company Janssen-Cilag Ltd
BNF chapter Malignant disease & immunosuppression
Submission type Limited
Status Recommended
Advice number 3812
NMG meeting date 07/11/2012
AWMSG meeting date 12/12/2012
Ratification by Welsh Government 16/01/2013
Date of issue 23/01/2013
Date of last review November 2022
Further information

This appraisal recommendation was reviewed in November 2022. No new evidence was identified that is likely to significantly affect the current recommendation. Therefore, this recommendation has been transferred to AWMSG’s static list of medicine recommendations

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