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atorvastatin (Lipitor®)

 

Following a limited submission

AWMSG advice

Status: Recommended

Atorvastatin (Lipitor®) chewable tablets are recommended as an option for use within NHS Wales:

  • As an adjunct to diet for reduction of elevated total cholesterol (total-C), LDL-cholesterol (LDL-C), apolipoprotein B, and triglycerides in adults, adolescents and children aged 10 years or older with primary hypercholesterolaemia including familial hypercholesterolaemia (heterozygous variant) or combined (mixed) hyperlipidaemia (corresponding to types IIa and IIb of the Fredrickson classification) when response to diet and other non-pharmacological measures is inadequate.
  • To reduce total-C and LDL-C in adults with homozygous familial hypercholesterolaemia as an adjunct to other lipid-lowering treatments (e.g. LDL apheresis) or if such treatments are unavailable.
  • For the prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event, as an adjunct to correction of other risk factors.
 Final Recommendation: atorvastatin (Lipitor) 1480 (PDF, 342Kb)
 Appraisal Report: atorvastatin (Lipitor) 1480 (PDF, 222Kb)

Medicine details

Medicine name atorvastatin (Lipitor®)
Formulation 5 mg, 10 mg, 20 mg, 40 mg chewable tablet
Reference number 1480
Indication

As an adjunct to diet for reduction of elevated total cholesterol (total-C), LDL-cholesterol (LDL-C), apolipoprotein B, and triglycerides in adults, adolescents and children aged 10 years or older with primary hypercholesterolaemia including familial hypercholesterolaemia (heterozygous variant) or combined (mixed) hyperlipidaemia (corresponding to Types IIa and IIb of the Fredrickson classification) when response to diet and other nonpharmacological measures is inadequate.

To reduce total-C and LDL-C in adults with homozygous familial hypercholesterolaemia as an adjunct to other lipid-lowering treatments (e.g. LDL apheresis) or if such treatments are unavailable.

Prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event, as an adjunct to correction of other risk factors

Company Pfizer Ltd
BNF chapter Cardiovascular system
Submission type Limited
Status Recommended
Advice number 1112
NMG meeting date 28/03/2012
AWMSG meeting date 09/05/2012
Ratification by Welsh Government 18/06/2012
Date of issue 19/06/2012
Date of last review August 2022
Further information

This appraisal recommendation was reviewed in August 2022. No new evidence was identified that is likely to significantly affect the current recommendation. Therefore, this recommendation has been transferred to AWMSG’s static list of medicine recommendations

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