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trastuzumab (Herceptin®)

 

Following a limited submission

AWMSG advice

Status: Recommended

Trastuzumab (Herceptin®) is recommended as an option for the treatment of patients with human epidermal growth factor receptor 2 (HER2)-positive early breast cancer. This submission covers the licence extensions for treatment with trastuzumab:

  • following adjuvant chemotherapy with doxorubicin and cyclophosphamide, in combination with paclitaxel or docetaxel;
  • in combination with adjuvant chemotherapy consisting of docetaxel and carboplatin.

AWMSG is of the opinion that trastuzumab (Herceptin®) is suitable for specialist only prescribing within NHS Wales for the above indication.

 Final Recommendation: trastuzumab (Herceptin) 1066 (PDF, 331Kb)
 Appraisal Report: trastuzumab (Herceptin) 1066 (PDF, 90Kb)

Medicine details

Medicine name trastuzumab (Herceptin®)
Formulation powder for concentrate for solution for infusion
Reference number 1066
Indication

Treatment of patients with HER2-positive early breast cancer following adjuvant chemotherapy with doxorubicin and cyclophosphamide, in combination with paclitaxel or docetaxel. Treatment of patients with HER2-positive early breast cancer in combination with adjuvant chemotherapy consisting of docetaxel and carboplatin

Company Roche Products Ltd
BNF chapter Malignant disease & immunosuppression
Assessment type Limited
Status Recommended
Advice number 0312
NMG meeting date 04/01/2012
AWMSG meeting date 08/02/2012
Ratification by Welsh Government 16/05/2012
Date of issue 18/05/2012
Date of last review 30/08/2016
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