Medicine details

For the treatment of adult patients with germline BRCA1 or 2 mutations, who have HER2-negative locally advanced or metastatic breast cancer. Patients should have been previously treated with an anthracycline and/or a taxane in the (neo) adjuvant, locally advanced or metastatic setting unless patients were not suitable for these treatments. Patients with hormone receptor-positive breast cancer should have been treated with a prior endocrine-based therapy, or be considered unsuitable for endocrine-based therapy

TA952: Talazoparib for treating HER2-negative advanced breast cancer with germline BRCA mutations