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sodium valproate (Episenta®)

 

Following a limited submission

AWMSG advice

Status: Recommended

Sodium valproate (Episenta®) is recommended as an option for use within NHS Wales for the treatment of manic episode in bipolar disorder when lithium is contraindicated or not tolerated. The continuation of treatment after manic episode could be considered in patients who have responded to sodium valproate (Episenta®) for acute mania. AWMSG is of the opinion that sodium valproate (Episenta®) may be suitable for shared care within NHS Wales.

 Final Recommendation: sodium valproate (Episenta) 1178 (PDF, 193Kb)
 Appraisal Report: sodium valproate (Episenta) 1178 (PDF, 45Kb)

Medicine details

Medicine name sodium valproate (Episenta®)
Formulation 150 mg, 300 mg, 500 mg prolonged-release capsule, 1000 mg prolonged-release granules
Reference number 1178
Indication

Treatment of manic episode in bipolar disorder when lithium is contraindicated or not tolerated. The continuation of treatment after manic episode could be considered in patients who have responded to sodium valproate for acute mania

Company Beacon Pharmaceuticals Ltd
BNF chapter Central nervous system
Submission type Limited
Status Recommended
Advice number 2111
NMG meeting date 03/11/2011
AWMSG meeting date 07/12/2011
Ratification by Welsh Government 09/01/2012
Date of issue 12/01/2012
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