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plerixafor (Mozobil®)

 

Following a limited submission

AWMSG advice

Status: Recommended

Plerixafor (Mozobil®) is recommended for use within NHS Wales in combination with granulocyte colony stimulating factor (G-CSF) to enhance mobilisation of haematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in children aged ≥ 1 to <18 years with lymphoma or solid malignant tumours either:

  • pre-emptively, when circulating stem cell count on the predicted day of collection after adequate mobilization with G-CSF (with or without chemotherapy) is expected to be insufficient with regards to desired haematopoietic stem cells yield, or;
  • who previously failed to collect sufficient haematopoietic stem cells.
 Final Recommendation: plerixafor (Mozobil) 3297 (PDF, 209Kb)
 Appraisal Report: plerixafor (Mozobil) 3297 (PDF, 101Kb)

Medicine details

Medicine name plerixafor (Mozobil®)
Formulation 20 mg/ml solution for injection
Reference number 3297
Indication

In combination with granulocyte-colony stimulating factor (G-CSF) to enhance mobilisation of haematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in children aged 1 to less than 18 years with lymphoma or solid malignant tumours, either: pre-emptively, when circulating stem cell count on the predicted day of collection after adequate mobilization with G-CSF (with or without chemotherapy) is expected to be insufficient with regards to desired hematopoietic stem cells yield; or who previously failed to collect sufficient haematopoietic stem cells

Company Sanofi
BNF chapter Nutrition & blood
Assessment type Limited
Status Recommended
Advice number 0120
NMG meeting date 08/01/2020
AWMSG meeting date 11/02/2020
Date of issue 14/02/2020
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