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pembrolizumab (Keytruda®)

 

Status: Excluded due to NICE appraisal

Product meets AWMSG exclusion criteria due to NICE appraisal TA914: Pembrolizumab for previously treated endometrial, biliary, colorectal, gastric or small intestine cancer with high microsatellite instability or mismatch repair deficiency

Medicine details

Medicine name pembrolizumab (Keytruda®)
Formulation 5 mg/mL concentrate for solution for infusion
Reference number 4945
Indication

Monotherapy for the treatment of the following MSI H or dMMR tumours in adults with: unresectable or metastatic colorectal cancer after previous fluoropyrimidine based combination therapy; advanced or recurrent endometrial carcinoma, who have disease progression on or following prior treatment with a platinum containing therapy in any setting and who are not candidates for curative surgery or radiation; unresectable or metastatic gastric, small intestine, or biliary cancer, who have disease progression on or following at least one prior therapy

Company Merck Sharp & Dohme Ltd
BNF chapter Malignant disease & immunosuppression
Assessment type N/A
Status Excluded due to NICE appraisal
Date of issue 30/09/2022
NICE guidance

TA914: Pembrolizumab for previously treated endometrial, biliary, colorectal, gastric or small intestine cancer with high microsatellite instability or mismatch repair deficiency

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