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pegylated liposomal irinotecan (Onivyde®)

 

Status: Excluded due to NICE appraisal

Product meets AWMSG exclusion criteria due to NICE appraisal TA440: Pegylated liposomal irinotecan for treating pancreatic cancer after gemcitabine. This medicine was considered by AWMSG Scrutiny Panel on 7th August 2025. It was considered not suitable for assessment by LOWMAG (AWTTC ref 7160).

Medicine details

Medicine name pegylated liposomal irinotecan (Onivyde®)
Formulation 5.0 mg/ml concentrate for solution for infusion
Reference number 1630
Indication

Treatment of metastatic adenocarcinoma of the pancreas, in combination with 5-fluorouracil (5-FU) and leucovorin (LV), in adult patients who have progressed following gemcitabine based therapy

Company Servier Laboratories Ltd
BNF chapter Malignant disease & immunosuppression
Assessment type N/A
Status Excluded due to NICE appraisal
Date of issue 31/08/2016
NICE guidance

TA440: Pegylated liposomal irinotecan for treating pancreatic cancer after gemcitabine

Further information

This medicine was considered by AWMSG scrutiny panel on 7th August 2025. 

Pegylated liposomal irinotecan (Onivyde®) in conjunction with chemotherapy after progression on gemcitabine-based therapy is not suitable for assessment via the Licensed Medicines One Wales Medicines Assessment Group (LOWMAG).

There were no significant new factors which would change the original NICE decision.

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