Status: One Wales interim decision | |
Using the agreed starting and stopping criteria, infliximab can be made available within NHS Wales for the treatment of immune checkpoint inhibitor induced grade 3-4 enterocolitis, where symptoms have not responded to first line immunosuppression with corticosteroids. Infliximab should be prescribed on the basis of lowest acquisition cost. The risks and benefits of the off-label use of infliximab for this indication should be clearly stated and discussed with the patient to allow informed consent. Providers should consult the relevant guidelines on prescribing unlicensed medicines before any off-label medicines are prescribed. This advice will be reviewed after 12 months or earlier if new evidence becomes available. |
|
Medicine details |
|
Medicine name | One Wales infliximab |
Formulation | powder for solution for infusion |
Reference number | OW21 |
Indication | Treatment of immune checkpoint inhibitor induced grade 3-4 enterocolitis, where symptoms have not responded to first line immunosuppression with corticosteroids |
Company | various |
BNF chapter | Gastro-intestinal system |
Submission type | One Wales |
Status | One Wales interim decision |
Advice number | OW21 |
Date of issue | 02/02/2023 |