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olanzapine (ZypAdhera®)

 

Status: Recommended with restrictions

Olanzapine (ZypAdhera®) is recommended as an option for restricted use within NHS Wales. Olanzapine (ZypAdhera®) is licensed for the maintenance treatment of adult patients with schizophrenia sufficiently stabilised during acute treatment with oral olanzapine. Olanzapine (ZypAdhera®) is restricted for use in a subpopulation of patients more appropriately managed with a long acting injection formulation because of difficulties adhering to an oral olanzapine regimen, indicated by recurrent relapse or exacerbation of symptoms. Olanzapine (ZypAdhera®) is not recommended for use within NHS Wales outside of this subpopulation.

 Final Recommendation: olanzapine (ZypAdhera) 2991 (PDF, 269Kb)
 Appraisal Report: olanzapine (ZypAdhera) 2991 (PDF, 661Kb)

Medicine details

Medicine name olanzapine (ZypAdhera®)
Formulation 210 mg, 300 mg, 405 mg powder and solvent for prolonged-release suspension for injection
Reference number 2991
Indication

Maintenance treatment of adult patients with schizophrenia sufficiently stabilised during acute treatment with oral olanzapine

Company Eli Lilly & Co Ltd
BNF chapter Central nervous system
Submission type Resubmission
Status Recommended with restrictions
Advice number 1516
NMG meeting date 11/05/2016
AWMSG meeting date 15/06/2016
Ratification by Welsh Government 26/07/2016
Date of issue 27/07/2016
Date of last review 01/08/2019
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