100 mg losartan potassium/12.5 mg hydrochlorothiazide (Cozaar® – Comp 100/12.5) has not been endorsed for use within NHS Wales for the treatment of hypertension in patients whose blood pressure is not adequately controlled on hydrochlorothiazide or losartan monotherapy. The holder of the marketing authorisation has not made a submission to AWMSG for the appraisal of 100 mg losartan potassium/12.5 mg hydrochlorothiazide (Cozaar®–Comp 100/12.5) in the above indication. As a result, AWMSG cannot advise the Minister for Health and Social Services whether this medicine should be available for use within NHS Wales.