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c1 inhibitor (human) (Cinryze®)

 

Following a limited submission

AWMSG advice

Status: Recommended

C1 inhibitor (human) (Cinryze®) is recommended as an option for use within NHS Wales for the treatment and pre-procedure prevention of angioedema attacks in adults, adolescents and children (2 years old and above) with hereditary angioedema (HAE); routine prevention of angioedema attacks in adults, adolescents and children (6 years old and above) with severe and recurrent attacks of HAE, who are intolerant to or insufficiently protected by oral prevention treatments, or patients who are inadequately managed with repeated acute treatment.

 Final Recommendation: c1 inhibitor (human) (Cinryze) 3295 (PDF, 342Kb)
 Appraisal Report: c1 inhibitor (human) (Cinryze) 3295 (PDF, 1.2Mb)

Medicine details

Medicine name c1 inhibitor (human) (Cinryze®)
Formulation 500 international units / 5ml powder and solvent for solution for injection
Reference number 3295
Indication

Treatment and pre-procedure prevention of angioedema attacks in adults, adolescents and children (2 years old and above) with hereditary angioedema (HAE); routine prevention of angioedema attacks in adults, adolescents and children (6 years old and above) with severe and recurrent attacks of HAE, who are intolerant to or insufficiently protected by oral prevention treatments, or patients who are inadequately managed with repeated acute treatment

Company Shire Pharmaceuticals Ltd
BNF chapter Respiratory system
Submission type Limited
Status Recommended
Advice number 2117
NMG meeting date 06/09/2017
AWMSG meeting date 11/10/2017
Date of issue 19/10/2017
Date of last review October 2020
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