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bevacizumab (Avastin®)

 

Status: Recommended with restrictions

Bevacizumab (Avastin®) is recommended as an option for restricted use within NHS Wales for use in combination with paclitaxel and cisplatin for the treatment of adult patients with persistent, recurrent, or metastatic carcinoma of the cervix.

Bevacizumab (Avastin®) is not recommended for use within NHS Wales for use in combination with paclitaxel and topotecan in patients who cannot receive platinum therapy, for the treatment of adult patients with persistent, recurrent, or metastatic carcinoma of the cervix.

This recommendation applies only in circumstances where the approved Patient Access Scheme (PAS) is utilised or where the list/contract price is equivalent to or lower than the PAS price.

 Final Recommendation: bevacizumab (Avastin) 5044 (PDF, 426Kb)
 Appraisal Report: bevacizumab (Avastin) 5044 (PDF, 317Kb)

Medicine details

Medicine name bevacizumab (Avastin®)
Formulation 25 mg/ml concentrate for solution for infusion
Reference number 5044
Indication

In combination with paclitaxel and cisplatin or, alternatively, paclitaxel and topotecan in patients who cannot receive platinum therapy, for the treatment of adult patients with persistent, recurrent, or metastatic carcinoma of the cervix

Company Roche Products Ltd
BNF chapter Malignant disease & immunosuppression
Submission type Resubmission
Status Recommended with restrictions
Advice number 1122
NMG meeting date 11/05/2022
AWMSG meeting date 15/06/2022
Date of issue 17/06/2022
Commercial arrangement PAS
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