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argatroban (Exembol®)

 

Following a full submission

AWMSG advice

Status: Recommended

Argatroban (Exembol®) is recommended as an option for use within NHS Wales for anticoagulation in adult patients with heparin-induced thrombocytopenia type II who require parenteral antithrombotic therapy. The diagnosis should be confirmed by the HIPAA (heparin induced platelet activation assay) or an equivalent test. However, such confirmation must not delay the start of treatment.

 Final Recommendation: argatroban (Exembol) 1405 (PDF, 305Kb)
 Appraisal Report: argatroban (Exembol) 1405 (PDF, 261Kb)

Medicine details

Medicine name argatroban (Exembol®)
Formulation 100 mg/ml concentrate for solution for infusion
Reference number 1405
Indication

Anticoagulation in adult patients with heparin-induced thrombocytopenia type II who require parenteral antithrombotic therapy. The diagnosis should be confirmed by the HIPAA (heparin induced platelet activation assay) or an equivalent test.  However, such confirmation must not delay the start of treatment

Company Mitsubishi Tanabe Pharma Europe Ltd
BNF chapter Cardiovascular system
Submission type Full
Status Recommended
Advice number 4312
NMG meeting date 07/11/2012
AWMSG meeting date 12/12/2012
Ratification by Welsh Government 16/01/2013
Date of issue 23/01/2013
Date of last review August 2022
Further information

This appraisal recommendation was reviewed in August 2022. No new evidence was identified that is likely to significantly affect the current recommendation. Therefore, this recommendation has been transferred to AWMSG’s static list of medicine recommendations

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